File:Granuloma inguinale01.jpeg

This was a very large erosive cutaneous lesion in the perineal region of this patient, which had been diagnosed as Donovanosis, otherwise known as granuloma inguinale, a genital ulcerative disease caused by the Gram-negative bacterium, Klebsiella granulomatis, formerly known as Calymmatobacterium granulomatis, and even earlier Donovania granulomatis. The causative organism is difficult to culture, and diagnosis requires visualization of dark-staining Donovan bodies on tissue crush preparation from a biopsy. Created by Samuel Freire da Silva, MD in homage to The Master And Professor Delso Bringel Calheiros. Image adapted with permission from Dermatology Atlas: http://www.atlasdermatologico.com.br/disease.jsf?diseaseId=109