Sandbox: ATL

Most patients with medulloblastoma are initially asymptomatic. If left untreated, most of the patients with medulloblastoma will develop ataxia, nystagmus, and positional dizziness within a few months. The clinical course is aggressive with a median survival of less than 12 months in the acute and lymphoma forms.

high lactate dehydrogenase (LDH) high leukemic counts hypercalcemia poor clinical performance status