Glomus tumor natural history
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
If left untreated, 20% of patients with glomus tumors may progress to develop [manifestation 1], [manifestation 2]
Natural History
If left untreated, patients with glomus tumors may progress to develop nail deformities
Prognosis
The most common adverse effect is pain, which is usually associated with solitary lesions. Multiple tumors are less likely to be painful. In one report, a patient with more than 400 glomus tumors had thrombocytopenia as a result of platelet sequestration (ie, Kasabach-Merritt syndrome). Malignant glomus tumors, or glomangiosarcomas, are extremely rare and usually represent a locally infiltrative malignancy. However, metastases do occur and are usually fatal.
Patients who have surgery or radiation tend to do well.
Complications
- Nail discoloration
- Nail deformity,
- Recurrence
- Recurrence is thought to be a result of incomplete excision or, in the case of late recurrence, development of a new lesion at or near the excision site. Excision of the capsule of the tumor is required to prevent local recurrence.[1]