Desmoid tumor natural history, complications, and prognosis

Desmoid tumor Microchapters
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Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Desmoid tumor from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
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Cost-Effectiveness of Therapy
Future or Investigational Therapies
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Case #1

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]

Overview

If left untreated, desmoid tumor produces few symptoms early in the course. Common complications of desmoid tumor include progression to agressive fibromatosis, involvement of intra abdominal viscera and metastasis. The prognosis varies with the associated disease of desmoid tumor. Desmoid tumor associated with FAP has the most unfavorable prognosis.

Natural history

• If left untreated, desmoid tumor produces few symptoms early in the course.

Complications

Common complications of desmoid tumor include:

• Progression to aggressive fibromatosis
• Involvement of intraabdominal organs
• Metastasis

Prognosis

Desmoid tumor associated with familial adenomatous polyposis has the most unfavorable prognosis.