MALT lymphoma natural history
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Natural History
Many people are diagnosed with localized or early stage disease that has not spread elsewhere in the body. MALT lymphomas are usually slow growing (indolent), but some can be high grade. They often remain in the area in which they started for a long period of time. Rarely, MALT lymphomas can change (transform) into a more aggressive large cell lymphoma.
Prognosis
- The prognosis is good, and the 10-year survival rate for gastric MALT lymphoma is approximately 90% with a disease-free survival of approximately 70%.[1]
- However, in rare instances, MALT lymphoma can progress and transform into aggressive high-grade tumors, such as extranodal diffuse large B cell lymphoma (eDLBCL), whereby the 10-year survival rate drops to approximately 42%.
References
- ↑ Troppan, Katharina; Wenzl, Kerstin; Neumeister, Peter; Deutsch, Alexander (2015). "Molecular Pathogenesis of MALT Lymphoma". Gastroenterology Research and Practice. 2015: 1–10. doi:10.1155/2015/102656. ISSN 1687-6121.