Trichinosis laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Danitza Lukac

Overview

A blood test indicating eosinophilia, elevated muscle enzymes and anti trichinella IgG or muscle biopsy can identify trichinosis.[1][2]

Laboratory Findings

Blood test:

  • Eosinophilia:
    • Appears 2 or 5 weeks after infection
    • It is related with severity of myalgia
    • Gets higher in patients with neurological complications
    • A great decrease of eosinophils in patients with complicated trichinosis is considered to be a bad indicator for the disease prognosis
  • Elevated muscle enzyme:
    • Creatinine phosphokinase, lactate dehydrogenase, and aldolase
    • Appears 2 or 5 weeks after infection
  • Anti trichinella antibodies IgG:
    • 12 to 60 days after infection
    • ELISA, indirect fluorescent antibody test (IFA) and Western blot can be used to find anti-Trichinella IgG[1]

References

  1. 1.0 1.1 Gottstein B, Pozio E, Nöckler K (2009). "Epidemiology, diagnosis, treatment, and control of trichinellosis". Clin Microbiol Rev. 22 (1): 127–45, Table of Contents. doi:10.1128/CMR.00026-08. PMC 2620635. PMID 19136437.
  2. Trichinosis. Wikipedia. https://en.wikipedia.org/wiki/Trichinosis. Accessed on January 22, 2016


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