Histoplasmosis chest x ray

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Serge Korjian M.D.

Chest X Ray

• Most patients with histoplasmosis (up to 70%) are thought to have normal chest radiographs.
• Where there are findings these can be non-specific to a range of infectious or inflammatory disorders and histoplasmosis is considered in the differential if the patient is known to have travelled in endemic regions.
• The particular imaging features are related to the timeline of presentation and the patient's ability to mount an immune response.
• Acute histoplasmosis may be associated with airspace shadowing with consolidation involving multiple lung segments or lobes similar to bacterial pneumonia
• Pleural effusions are also possible, but uncommon.
• Patients with chronic histoplasmosis may present with pulmonary nodules.