Extramammary Paget's disease epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Extramammary Paget's disease is rare and the precise incidence is unknown. Extramammary Paget's disease commonly affects individuals 50-60 years of age. Females are more commonly affected with the disease than males. The female to male ratio is approximately 4.5-3 to 1. It usually affects individuals of the Caucasian race, but it may occur in other races.[1]
Epidemiology and Demographics
Vulval extramammary Paget's disease represents 1% to 5% of all vulval malignancies, with a peak age incidence of 65 years.[2][3]
Incidence
Extramammary Paget's disease is rare and the precise incidence is unknown.
Prevalence
The prevalence of invasive extramammary Paget's disease is estimated to occur in 5-25% of patients.
Age
Extramammary Paget's disease commonly affects individuals 50-60 years of age. The median age of incidence of vulval disease was 65 years. The median age for a diagnosis of scrotal disease was 70.4 years; for penile disease, it was 73.6 years. After exclusion of vulvar disease, extramammary Paget's disease was most commonly seen in the scrotum and penis, followed by the anorectal area.[4]
Gender
Females are more commonly affected with extramammary Paget's disease than males. The female to male ratio is approximately 4.5-3 to 1.[1]
Race
Extramammary Paget's disease usually affects individuals of the Caucasian race, but it may occur in other races.[5]
References
- ↑ 1.0 1.1 Chanda JJ (1985). "Extramammary Paget's disease: prognosis and relationship to internal malignancy". J Am Acad Dermatol. 13 (6): 1009–14. PMID 3001158.
- ↑ Curtin JP, Rubin SC, Jones WB, Hoskins WJ, Lewis JL (1990). "Paget's disease of the vulva". Gynecol Oncol. 39 (3): 374–7. PMID 2175288.
- ↑ Lloyd J, Flanagan AM (2000). "Mammary and extramammary Paget's disease". J Clin Pathol. 53 (10): 742–9. PMC 1731095. PMID 11064666.
- ↑ Moretto, P.; Nair, V.J.; El Hallani, S.; Malone, S.; Belanger, E.; Morash, C.; Canil, C.M. (2013). "Management of penoscrotal extramammary Paget disease: case series and review of the literature". Current Oncology. 20 (4): 311. doi:10.3747/co.20.1353. ISSN 1718-7729.
- ↑ Zollo, J.D.; Zeitouni, N.C. (2000). "The Roswell Park Cancer Institute experience with extramammary Paget's disease". British Journal of Dermatology. 142 (1): 59–65. doi:10.1046/j.1365-2133.2000.03242.x. ISSN 0007-0963.