Langerhans cell histiocytosis physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Langerhans cell histiocytosis patients often appear cachectic. Physical examination of patients with Langerhans cell histiocytosis is usually remarkable for scaly erythematous lesions located on the scalp and extremities, localized bone tenderness, and hepatosplenomegaly.

Physical Findings

General Appearance

• Langerhans cell histiocytosis patients often appear cachectic

Vital Signs

• Low-grade fever

HEENT

• Scaly erythematous scalp lesions

• 
  Langerhans cell histiocytosis. Adapted from Dermatology Atlas.
• 
  Langerhans cell histiocytosis. Adapted from Dermatology Atlas.
• 
  Langerhans cell histiocytosis. Adapted from Dermatology Atlas.
• 
  Langerhans cell histiocytosis. Adapted from Dermatology Atlas.
• 
  Langerhans cell histiocytosis. Adapted from Dermatology Atlas.
• 
  Langerhans cell histiocytosis. Adapted from Dermatology Atlas.

Abdomen

• Hepatomegaly
• Splenomegaly

Extremities

• Scaly erythematous cutaneous lesions
• Localized bone tenderness

• 
  Langerhans cell histiocytosis. Adapted from Dermatology Atlas.
• 
  Langerhans cell histiocytosis. Adapted from Dermatology Atlas.
• 
  Langerhans cell histiocytosis. Adapted from Dermatology Atlas.

References

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