Mesothelioma differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2], Sujit Routray, M.D. [3]
Overview
Mesothelioma must be differentiated from pleural effusion, lung cancer, pulmonary tuberculosis, peritoneal tuberculosis, pseudomyxoma peritonei, constrictive pericarditis, ovarian cystadenoma, and mesothelial hyperplasia of the testis.[1][2][3][4][5][6][7]
Differentiating Mesothelioma from other Diseases
Differentiating Pleural Mesothelioma from other Diseases
Pleural mesothelioma must be differentiated from:[1][2]
- Pleural effusion
- Benign asbestos-related pleural disease
- Peripheral bronchogenic carcinoma
- Pleural fibrosis from infective/inflammatory source (e.g. actinomycetes, tuberculosis)
- Primary pleural tumors
- Secondary lesions that can involve the pleura
- Pleural metastases
- Thymoma with pleural invasion
- Pericardial tumors with pleural invasion
- Ewing sarcoma of chest wall with pleural invasion
Differentiating Peritoneal Mesothelioma from other Diseases
Peritoneal mesothelioma must be differentiated from:[3][4]
- Peritoneal carcinomatosis
- Pseudomyxoma peritonei
- Lymphoma with peritoneal involvement
- Peritoneal involvement with tuberculosis
- Mesenteric panniculitis
- Primary peritoneal adenomatoid tumor
- Primary peritoneal papillary serous carcinoma
- Primary peritoneal serous borderline tumor
- Diffuse peritoneal leiomyomatosis
- Desmoplastic small round cell tumor arising from the peritoneum
- Solitary fibrous tumor arising the peritoneum
- Peritoneal lymphangioma
- Peritoneal inclusion cyst
Differentiating Pericardial Mesothelioma from other Diseases
Pericardial mesothelioma must be differentiated from:[5]
- Heart failure
- Coronary heart disease
- Constrictive pericarditis
- Cardiomyopathy
- Tuberculosis pericarditis
- Cardiac tamponade
- Intra-atrial myxoma
Differentiating Multicystic Mesothelioma from other Diseases
Multicystic mesothelioma must be differentiated from:[6]
- Abdominopelvic cystic lymphangioma
- Ovarian cystadenoma
- Ovarian cystadenocarcinoma
- Endometriosis
- Cystic teratoma
- Cystic mucinous tumor of pancreas
Differentiating Tunica Vaginalis Testis Mesothelioma from other Diseases
Tunica vaginalis testis mesothelioma must be differentiated from:[7]
- Mesothelial hyperplasia of the testis
- Adenomatoid tumor of the testis
- Rete testis adenocarcinoma
- Serous papillary tumors of the testis and epididymis
- Pleomorphic rhabdomyosarcoma
- Malignant fibrous histiocytoma
- Germ cell tumors of the testis
References
- ↑ 1.0 1.1 Differential diagnosis of mesothelioma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/mesothelioma. Accessed on February 12, 2016
- ↑ 2.0 2.1 Dr Yuranga Weerakkody et al. Radiopaedia 2016. http://radiopaedia.org/articles/pleural-tumours. Accessed on February 12, 2016
- ↑ 3.0 3.1 Differential diagnosis of peritoneal mesothelioma. Dr Alexandra Stanislavsky et al. Radiopaedia 2016. http://radiopaedia.org/articles/peritoneal-mesothelioma. Accessed on February 12, 2016
- ↑ 4.0 4.1 Primary peritoneal neoplasms. Dr Praveen Jha and Radswiki et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-peritoneal-neoplasms. Accessed on February 12, 2016
- ↑ 5.0 5.1 Seek a Second Opinion to Avoid Misdiagnosis of Pericardial Mesothelioma. Asbestos.com 2016. http://www.asbestos.com/mesothelioma/pericardial.php. Accessed on February 12, 2016
- ↑ 6.0 6.1 Differential diagnosis of multicystic mesothelioma. Dr Aditya Shetty and Dr Yuranga Weerakkody et al. Raiopaedia 2016. http://radiopaedia.org/articles/multicystic-mesothelioma. Accessed on February 12, 2016
- ↑ 7.0 7.1 Chekol, Seble S; Sun, Chen-Chin (2012). "Malignant Mesothelioma of the Tunica Vaginalis Testis: Diagnostic Studies and Differential Diagnosis". Archives of Pathology & Laboratory Medicine. 136 (1): 113–117. doi:10.5858/arpa.2010-0550-RS. ISSN 0003-9985.