Extranodal NK-T-cell lymphoma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

Extranodal NK-T-cell lymphoma may be classified according to WHO into 2 subtypes: NK cell-derived neoplasms, namely, aggressive NK cell leukemia and extranodal NK/T-cell lymphoma, nasal type. Based on the organ involvement, extranodal NK-T-cell lymphoma may be classified into extranodal NK-T-cell lymphoma, nasal type and extranodal NK-T-cell lymphoma, extra nasal type.

Classification

Extranodal NK-T-cell lymphoma may be classified according to WHO into 2 subtypes:

• NK cell-derived neoplasms, namely, aggressive NK cell leukemia
• Extranodal NK/T-cell lymphoma, nasal type

Based on the organ involvement, extranodal NK-T-cell lymphoma may be classified into:

• Extranodal NK-T-cell lymphoma, nasal type
• Extranodal NK-T-cell lymphoma, extra nasal type

Extranodal NK-T-cell lymphoma classification

Name	Description
Extranodal NK-T-cell lymphoma, nasal type	Most commonly affects the nose or nasal passages and paranasal sinuses
Extranodal NK-T-cell lymphoma, extra nasal type	Can affect the: Skin Testicles Soft tissues Kidneys Brain or spinal cord (central nervous system) Respiratory tract Gastrointestinal tract

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