Primary central nervous system lymphoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Epidemiology and Demographics
Prevalence
- Primary central nervous system lymphoma constitutes approximately 3%-4% of all primary brain tumors.[1]
- Primary CNS lymphoma constitues approximately 1%-2% of all lymphomas.[1]
Incidence
- The overall incidence rate of primary central nervous system lymphoma is 0.4 cases per 100,000 individuals per year.[1]
The incidence of PCNSL in the immunocompetent population has been reported to have increased more than 10-fold from 2.5 cases to 30 cases per 10 million population[2][3]. The cause for the increase in incidence of this disease in the immunocompetent population is unknown.
Age
Primary central nervous system lymphoma does not have predilections for any age group. In the immunocompetent population, PCNSL typically affects older patients in their 50's and 60's.
References
- ↑ 1.0 1.1 1.2 Manenti, G.; Di Giuliano, F.; Bindi, A.; Liberto, V.; Funel, V.; Garaci, F. G.; Floris, R.; Simonetti, G. (2013). "A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment". Case Reports in Radiology. 2013: 1–5. doi:10.1155/2013/916348. ISSN 2090-6862.
- ↑ Eby NL, Grufferman S, Flannelly CM, Schold SC, Jr., Vogel FS, Burger PC. Increasing incidence of primary brain lymphoma in the US. Cancer 1988;62(11):2461-2465
- ↑ Corn BW, Marcus SM, Topham A, Hauck W, Curran WJ, Jr. Will primary central nervous system lymphoma be the most frequent brain tumor diagnosed in the year 2000? Cancer 1997;79(12):2409-2413