Mucoepidermoid carcinoma differential diagnosis
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Differentiating Mucoepidermoid Carcinoma from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Mucoepidermoid carcinoma must be differentiated from other diseases that cause painless swelling, facial deformity, and facial numbness, such as Warthin's tumor, adenoid cystic carcinoma, benign mixed tumor (salivary glands), and metastasis.[1]
Differential Diagnosis
- The table below summarizes the findings that differentiate mucoepidermoid carcinoma from other conditions that cause painless swelling, facial deformity, and facial numbness or weakness.[1][2]
| Differential Diagnosis | Similar Features | Differentiating Features |
|---|---|---|
| Benign mixed tumor (salivary glands) | Painless parotid swelling and facial deformity | Histopathological findings |
| Warthin's tumor | Painless swelling and facial deformity | Multicentric presentation (20%), usually small in size (1-4 cm), highly associated with smoking |
| Adenoid cystic carcinoma | Local swelling | In adenoid cystic carcinoma, differentiating features include: tendency for perineural extension, distribution, and mainly occur in relation to the airways |
| Metastasis | Painless swelling, facial deformity, and facial numbness. | In metastasis, differentiating features include: primary tumor origin, and histopathological findings. |