Mast cell tumor differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Mast cell tumor must be differentiated from other diseases that cause elevated serum tryptase levels and cytopenia, such as: myelodysplastic syndrome, primary myelofibrosis, essential thrombocythemia, and chronic eosinophilic leukemia

Differential Diagnosis

• Achlorhydria
• Cutaneous Pseudolymphoma
• Dermatologic Manifestations of Herpes Simplex
• Epidermolysis Bullosa
• Lentigo
• Linear IgA Dermatosis

Mast cell tumor must be differentiated from other diseases that cause elevated serum tryptase levels and cytopenia, such as:

• Myelodysplastic syndrome
• Primary myelofibrosis
• Essential thrombocythemia
• Chronic eosinophilic leukemia
• Chronic myeloid leukemia
• Myelomastocytic leukemia
• Malignant lymphoma