Intensity of statin therapy in primary and secondary prevention
Template:Hypercholesterolemia Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The intensity of statin therapy is defined on the basis of the average expected LDL response to a specific statin and dose. High-intensity statin daily therapy lowers LDL by approximately ≥50%, moderate-intensity statin lowers LDL by approximately 30% to <50%, and lower-intensity statin lowers LDL by <30%.[1]
High-, Moderate-, and Low-Intensity Statin Therapy
| High-Intensity Statin Therapy | Moderate-Intensity Statin Therapy | Low-Intensity Statin Therapy |
| Atorvastatin (40†)–80 mg Rosuvastatin 20 (40) mg |
Atorvastatin 10 (20) mg Rosuvastatin (5) 10 mg Simvastatin 20–40 mg‡ Pravastatin 40 (80) mg Lovastatin 40 mg Fluvastatin XL 80 mg Fluvastatin 40 mg bid Pitavastatin 2–4 mg |
Simvastatin 10 mg Pravastatin 10–20 mg Lovastatin 20 mg Fluvastatin 20–40 mg Pitavastatin 1 mg |
References
- ↑ "2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults". Retrieved 13 November 2013.