Cirrhosis historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Charmaine Patel, M.D. [2] Aditya Govindavarjhulla, M.B.B.S. [3]
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Overview
The first description of the clinical picture and pathologic appearance of cirrhosis, was published in 1761. René Laennec coined the term "cirrhosis" in 1819.
Historical Perspective
- This transformation of the liver was identified by the first anatomic pathologist, Gianbattista Morgagni in his 500 autopsies published in 1761.
- Only in 1930, one hundred years later, however, the first theory as to the pathogenesis of this disorder was advanced by Roessle: parenchymal degeneration, regeneration and scarring.
- The word "cirrhosis" is a neologism that derives from Greek kirrhos, meaning "tawny" (the orange-yellow color of the diseased liver). René Laennec was the person who gave the known clinical enitity, the name "cirrhosis" in his 1819 work, during which he also describes the stethoscope.[1]
- The first description of primary biliary cirrhosis was reported in 1851 by Addison and Gull at Guy's Hospital Report, the title being "On a certain affectation of skin-vitiligoiedea-alpha plana-beta tuberosa". A few years later in 1892, Hanot reported "La cirrhosis hypertrophique avec ictere et chroniqe". Ahrens et al. first coined the term primary biliary cirrhosis in 1950. [2]
References
- ↑ Roguin A. Rene Theophile Hyacinthe Laennec (1781-1826): the man behind the stethoscope. Clin Med Res 2006;4:230-5. PMID 17048358.
- ↑ Heathcote EJ (2003). "Primary biliary cirrhosis: historical perspective". Clin Liver Dis. 7 (4): 735–40. PMID 14594128.