Orbital cellulitis differential diagnosis

Orbital cellulitis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]

Overview

Orbital cellulitis must be differentiated from preseptal cellulitis.

Differential Diagnosis

Orbital cellulitis may share common features or present similarly to other eye diseases with significantly varying management protocols. As such, the clinician must carefully consider the history, the presenting signs and symptoms, and cross reference the following differentials:

Infectious diseases

• Periorbital cellulitis
• Endophthalmitis
• Severe conjunctivitis
• Herpes Zoster Ophthalmicus
• Posterior Scleritis
• Mucormycosis, Aspergilliosis of the globe
• M.Tuberculosis of the globe

Vascular

• Cavernous sinus thrombosis
• Atriovenous fistula
• Orbital varices

Autoimmune/Inflammatory

• Exophthalmos
• Wegeners granulomatosis
• Sarcoidosis granuloma
• Orbital pseudotumor

Structural/Trauma

• Retrobulbar hematoma
• Mucocele
• Dermoid cyst

Neoplastic

• Metastatic carcinoma
• Neurofibroma
• Schwannoma
• Glioma
• Retinoblastoma
• Rhabdomyosarcoma
• Neuroblastoma
• Lymphoma
• Leukemia