St. Louis encephalitis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]; Contributor(s): Irfan Dotani [3], Vishnu Vardhan Serla M.B.B.S. [4]

Overview

Natural History

If left untreated, 40% of patients with St. Louis encephalitis may progress to develop severe neurological deficits such as deafness, hemiplegia, and aphasia.^[1]

Complications

Common complications of St. Louis encephalitis include:^[2]

Seizures
Coma
Disoreintation
Spastic paralysis

Severe complications of St. Louis encephalitis include:^[2]

Death
Hemorrhage

Prognosis

Prognosis is generally poor. Approximately 25-30% of patients progress to mortality. Among patients who survive, approximately 50% suffer severe neurological, cognitive, or psychological deficits.^[3]^[4]

References

↑ Meningitis and Encephalitis Fact Sheet. National Institute of Neurological Disorders and Stroke (2016). http://www.ninds.nih.gov/disorders/encephalitis_meningitis/detail_encephalitis_meningitis.htm#3083_9 Accessed on July 29, 2016.
↑ ^2.0 ^2.1 Flavivirus encephalitis. Radiopaedia.org (2015). http://radiopaedia.org/articles/flavivirus-encephalitis Accessed on July 29, 2016.
↑ Saint Louis Encephalitis. Centers for Disease Control, and Prevention (2010). http://www.cdc.gov/sle/ Accessed on July 29, 2016.
↑ Yellow Fever. MedlinePlus (2015). https://medlineplus.gov/ency/article/001365.htm Accessed on July 29, 2016.

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[NIHSLEV-1] Meningitis and Encephalitis Fact Sheet. National Institute of Neurological Disorders and Stroke (2016). http://www.ninds.nih.gov/disorders/encephalitis_meningitis/detail_encephalitis_meningitis.htm#3083_9 Accessed on July 29, 2016.

[FESLEV-2] 2.0 ^2.1 Flavivirus encephalitis. Radiopaedia.org (2015). http://radiopaedia.org/articles/flavivirus-encephalitis Accessed on July 29, 2016.

[SLE-3] Saint Louis Encephalitis. Centers for Disease Control, and Prevention (2010). http://www.cdc.gov/sle/ Accessed on July 29, 2016.

[YFSLEV-4] Yellow Fever. MedlinePlus (2015). https://medlineplus.gov/ency/article/001365.htm Accessed on July 29, 2016.

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