Differentiating erythrasma from other diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Erythrasma must be differentiated from other dermatological conditions that present with pain, erythema, edema, and blisters of the skin, as well as other systemic conditions such as fever, chills, fatigue, headache, and vomiting.

Differentiating Erythrasma from other Diseases

Erythrasma must be differentiated from other dermatological conditions that present with reddish-brown scales and [[itching], as well as other diseases resulting from corynebacteria infection.

Disease Findings
Psoriasis Presents with erythema and formation of silvery scales on the epidermis, resulting in itching and pain.[1] Differentiates from Erythrasma in that it is usually located throughout the entire body; Erythrasma usually manifests in skin folds of the armpit, groin, and perianal regions.[2]Psoriasis is an autoimmune disorder and is not caused by Corynebacteria; therapeutic options include topical corticosteroids, systemic anti-inflammatory therapies (such as methotrexate and cyclosporine), and UVA/UVB phototherapy.[2] Psoriasis is a chronic, recurrent condition; Erythrasma will usually resolve with sufficient treatment.
Dermatophytosis Presents with lesions that vary based on the location of the mycosis, but usually displays in a circular shape with erythema, scaling, and itching at the point of infiltration .[3] Differentiated by its mycotic cause. Treatment involves topical antifungal medication, including miconazole, clotrimazole, ketoconazole, terbinafine, naftifine, and butenafine.[4]
Candidiasis
Intertrigo
Contact dermatitis An inflammatory condition of the epidermis resulting from direct contact with an allergen or irritant. Contact dermatitis is similar to erysipelas due to the usual presentation of erythema, blisters, itching, pain, and discharge. Differentiated from erysipelas by its cause: an allergic response by contact to a specific surface or entity. There is no indication of bacterial infection. Common causes include chemicals from cosmetic and hygienic products, fabrics, metals, and animal hair or skin. Therapy involves avoiding the original cause and application of topical or oral corticosteroids and analgesics.[5]

References

  1. "Psoriasis: MedlinePlus".
  2. 2.0 2.1 Di Meglio P, Villanova F, Nestle FO (2014). "Psoriasis". Cold Spring Harb Perspect Med. 4 (8). doi:10.1101/cshperspect.a015354. PMC 4109580. PMID 25085957.
  3. Ely JW, Rosenfeld S, Seabury Stone M (2014). "Diagnosis and management of tinea infections". Am Fam Physician. 90 (10): 702–10. PMID 25403034.
  4. Kyle AA, Dahl MV (2004). "Topical therapy for fungal infections". Am J Clin Dermatol. 5 (6): 443–51. PMID 15663341.
  5. "Contact dermatitis: MedlinePlus Medical Encyclopedia".

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