Diphtheria differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Differentiating diphtheria from other diseases

Differentiating cutaneous diphtheria from other diseases

Cutaneous diphtheria due to Corynebacterium diphtheria must be differentiated from other bacteria and fungi that present with a shallow ulcer on the skin:

• Bacterial causes:
  • Pyoderma due to Staphylococcus aureus or Group A beta-hemolytic streptococci
  • Cutaneous Leishmaniasis
  • Cutaneous Anthrax due to Bacillus Anthracis
  • Cutaneous mycobacterial infections due to Mycobacterium tuberculosis, Mycobacterium marinum or Mycobacterium ulcerans

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