Candida vulvovaginitis classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Overview

Candida vulvovaginitis can be classified based on the duration, as well as the strain of Candida causing the infection.

Classification

Candida vulvovaginitis can be classified based on the duration, as well as the strain of Candida causing the infection.

Duration

Candida vulvovaginitis can be divided based on the duration of the infection into:[1][2][3][4]

  • Acute, uncomplicated: these are usually sporadic cases of Candida vulvovaginitis, which respond to topical anti-fungal therapy and have a high cure rate
  • Acute, complicated: symptoms are more severe than uncomplicated infections and typically require a combination of oral and topical anti-fungal treatment
  • Recurrent: defined as 4 or more cases of Candida vulvovaginitis per year, usually caused by the same strain of Candida. Treatment also requires a combination of oral and topical anti-fungal agents

Microbiology

Candida vulvovaginitis can also be divided based on the strain of Candida causing the infection:[3][5][6]

  • C. albicans: comprises the majority of cases of Candida vulvovaginitis
  • C. glabrata: it is the second most common causative pathogen
  • C. tropicalis
  • C. krusei
  • C. parapsilosis

References

  1. Eckert LO (2006). "Clinical practice. Acute vulvovaginitis". N. Engl. J. Med. 355 (12): 1244–52. doi:10.1056/NEJMcp053720. PMID 16990387.
  2. Sobel JD, Faro S, Force RW, Foxman B, Ledger WJ, Nyirjesy PR, Reed BD, Summers PR (1998). "Vulvovaginal candidiasis: epidemiologic, diagnostic, and therapeutic considerations". Am. J. Obstet. Gynecol. 178 (2): 203–11. PMID 9500475.
  3. 3.0 3.1 Sobel JD (2007). "Vulvovaginal candidosis". Lancet. 369 (9577): 1961–71. doi:10.1016/S0140-6736(07)60917-9. PMID 17560449.
  4. Vazquez JA, Sobel JD, Demitriou R, Vaishampayan J, Lynch M, Zervos MJ (1994). "Karyotyping of Candida albicans isolates obtained longitudinally in women with recurrent vulvovaginal candidiasis". J. Infect. Dis. 170 (6): 1566–9. PMID 7995997.
  5. Buscemi L, Arechavala A, Negroni R (2004). "[Study of acute vulvovaginitis in sexually active adult women, with special reference to candidosis, in patients of the Francisco J. Muñiz Infectious Diseases Hospital]". Rev Iberoam Micol. 21 (4): 177–81. PMID 15709796.
  6. Corsello S, Spinillo A, Osnengo G, Penna C, Guaschino S, Beltrame A, Blasi N, Festa A (2003). "An epidemiological survey of vulvovaginal candidiasis in Italy". Eur. J. Obstet. Gynecol. Reprod. Biol. 110 (1): 66–72. PMID 12932875.

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