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Candida auris Microchapters |
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Overview of Candida auris
Candida auris is a fungus, recently described as a rare cause of fungal infection with significant resistance to antifungal medications.[2] Candida auris isolates from north and south Indian hospitals, Japan and Korea were all found to be resistant to the antifungal medication fluconazole.[2] Some isolates were also noted to be resistant to flucytosine and voriconazole.[2] The high rate of therapeutic failure noted in cases of Candida auris fungemia poses significant concerns.[2] It's high potential for nosocomial horizontal transmission has been demonstrated.[3][4]An outbreak of fifty cases over a sixteen month period (April 2015-July2016) in a cardiothoracic center in London is the first reported case, and the largest outbreak in Europe.[4] It is recognized as a globally emerging fungal pathogen[4].
Historical Perspective
References
- ↑ 1.0 1.1 Center for Disease Control. wwww.cdc.gov/tb. Accessed on November 11th, 2016.
- ↑ 2.0 2.1 2.2 2.3 Chowdhary A, Anil Kumar V, Sharma C, Prakash A, Agarwal K, Babu R; et al. (2014). "Multidrug-resistant endemic clonal strain of Candida auris in India". Eur J Clin Microbiol Infect Dis. 33 (6): 919–26. doi:10.1007/s10096-013-2027-1. PMID 24357342.
- ↑ Calvo B, Melo AS, Perozo-Mena A, Hernandez M, Francisco EC, Hagen F; et al. (2016). "First report of Candida auris in America: Clinical and microbiological aspects of 18 episodes of candidemia". J Infect. 73 (4): 369–74. doi:10.1016/j.jinf.2016.07.008. PMID 27452195.
- ↑ 4.0 4.1 4.2 Schelenz S, Hagen F, Rhodes JL, Abdolrasouli A, Chowdhary A, Hall A; et al. (2016). "First hospital outbreak of the globally emerging Candida auris in a European hospital". Antimicrob Resist Infect Control. 5: 35. doi:10.1186/s13756-016-0132-5. PMC 5069812. PMID 27777756.