Familial combined hyperlipidemia
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Lipoprotein Disorders Microchapters |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Type IIB hyperlipoproteinemia
Overview
The high VLDL levels are due to overproduction of substrates, including triglycerides, acetyl-CoA, and an increase in B-100 synthesis. They may also be caused by the decreased clea== Historical Perspective ==
Historical perspective
- In 1967, Fredrickson using paper electrophosresis , classified lipoprotein disorder.[1]
Classification
- There is no established classification for familial combined hyperlipidemia.
Pathophysiology
Pathogenesis
Causes
The cause of familial combined hyperlipidemia remains genetic.
Differential diagnosis
Epidemiology and Demographics
Epidemiology
Demographics
Age
Gender
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
History and symptoms
Symptoms of
Physical examination
- Signs of Type
Laboratory findings
Molecular Genetic Testing
Treatment
Pregnancy Management
Investigative Therapies
Gene Therapy
Prevention
Secondary prevention
Prevention of complications
References
- ↑ Culliton BJ (1987). "Fredrickson's bitter end at Hughes". Science. 236 (4807): 1417–8. PMID 3296193.
Template:WikiDoc Sources rance of LDL. Prevalence in the population is 10%.