Ischemic stroke laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]

Overview

Laboratory Findings

Labortary tests may help determine the risk factors complications of ischemic stroke. Blood tests which may be performed include:

Blood test Test result Rationale
Complete blood count
  • May suggest underlying infection
  • Increased risk of thrombotic event
  • May increase the risk of bleeding in pateints eligible for thrombolytic therapy
Lipid profile
  • May increase the risk of thromboembolic event
PT/APTT/INR
  • Increased PT/APTT/INR
  • May increase the risk of bleeding in patients eligible for anticoagualant therapy
  • May suggest underlying coagulation disorder
BUN/Creatinine
  • Increased BUN and creatinine
  • Mild to moderate renal dysfunction is an independant risk factor for ischemic stroke
  • May be associated with poor prognosis in patients with ischemic stroke
Serum homocysteine level
  • Increased levels of serum homocysteine levels
  • May be associated with increased risk of thromboembolic event
Basic metabolic panel
  • Increased or decreased serum NA2+, K+, Ca2+
  • May mimic or complicate patients with ischemic stroke
HbA1C
  • Increased levels of HbA1c
  • May suggest control of diabetes in past few months
  • Increased levels associated with increased risk of ischemic stroke
  • May be associated with poor prognosis in patients with ischemic stroke
Blood glucose levels
  • Increased or decreased levels of blood glucose
  • Hyperglycemia is associated with poor prognosis of ischemic stroke
  • Hypoglycemia may complicate or mimic patients with ischemic stroke
*Cardiac enzymes
  • Increased serum levels of Trop I, Trop T, CK-MB
  • May suggest ongoing myocardial ischemia
Pregnancy test
  • Serum and urine B-HCG
  • Rule out pregnancy in all female patients with ischemic stroke since t-PA is a class C agent

References


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