Von Willebrand disease history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
History
Symptoms
The various types of vWD present with varying degrees of bleeding tendency. In general patients with vWD mainly present with the following:
- Mucosa-associated bleeding
- bleeding after surgery and trauma
This usually may manifest in the form of the following:
- Easy bruising
- Nosebleeds
- Oral cavity bleeding
- Bleeding after dental extraction/surgery
- Heavy menstrual periods
- Postpartum hemorrhage.
- Severe internal or joint bleeding is rare (which only occurs in type 3 vWD).
To make a diagnosis, there is usually personal or family history of bleeding and laboratory evidence of defective von Willebrand factor, factor VIII, or both.