Primary sclerosing cholangitis natural history, complications and prognosis
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Differentiating Primary sclerosing cholangitis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Natural History
Complications
Some of the complications of primary sclerosing cholangitis include:
- Osteoporosis: Patients with primary sclerosing cholangitis lose 1% of their bone mass every year.[1]
- Liver cirrhosis and end-stage liver disease (ESLD).
- Cholangiocarcinoma: the risk of cholangiocarcinoma in patients with primary sclerosing cholangitis is 400 times higher than the risk in the general population.
Prognosis
References
- ↑ Angulo P, Grandison GA, Fong DG, Keach JC, Lindor KD, Bjornsson E, Koch A (2011). "Bone disease in patients with primary sclerosing cholangitis". Gastroenterology. 140 (1): 180–8. doi:10.1053/j.gastro.2010.10.014. PMC 3043598. PMID 20955707.