Primary sclerosing cholangitis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
The most important risk factors associated with primary sclerosing cholangitis include family history and personal history of IBD.
Risk Factors
The most common risk factors associated with the development of primary sclerosing cholangitis are:[1][2]
- IBD: Primary sclerosing cholangitis is more associated with ulcerative colitis than Crohn's disease.
- Family history: those with siblings with primary sclerosing cholangitis are 9-39 times more likely to develop the disease than the general population.
References
- ↑ Lazaridis KN, LaRusso NF (2016). "Primary Sclerosing Cholangitis". N. Engl. J. Med. 375 (12): 1161–70. doi:10.1056/NEJMra1506330. PMID 27653566.
- ↑ Boonstra K, de Vries EM, van Geloven N, van Erpecum KJ, Spanier M, Poen AC, van Nieuwkerk CM, Witteman BJ, Tuynman HA, Naber AH, Kingma PJ, Beuers U, Ponsioen CY (2016). "Risk factors for primary sclerosing cholangitis". Liver Int. 36 (1): 84–91. doi:10.1111/liv.12894. PMID 26077553.