Dermatomyositis causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

The causes of dermatomyositis are not fully understood. Commonly cited causes include viral infection and autoimmune diseases. Other causes include oncologic malignancies and drug side effects.

Causes

Common Causes

• Antinuclear antibodies
• Autoantibodies
• Hla-b8
• Hla-dr3
• Hla-drw52
• Interferon-alpha
• Interferon-beta
• Interferon-gamma
• Coxsackie b virus
• Echovirus
• Hepatitis b vaccine
• Hiv
• Htlv-1
• Hypertrichosis
• Parvovirus
• Pyrexia of unknown origin
• Sterile pneumonitis
• Streptococcus
• Toxoplasma

Causes by Organ System

Cardiovascular	Pericarditis, Raynaud phenomenon, Statins, Vasculitis
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	Calcinosis cutis, Gottron papules, Photosensitivity of skin, Sclerosis of skin, Telangiectasia
Drug Side Effect	Carbimazole, Carticaine, Cimetidine, Cyclophosphamide, Penicillamine, Phenylbutazone, Phenytoin, Quinidine, Statins
Ear Nose Throat	Dysphagia, Dysphonia
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	Antinuclear antibodies, Autoantibodies, Hla-b8, Hla-dr3, Hla-drw52, Interferon-alpha, Interferon-beta, Interferon-gamma
Hematologic	Chronic myelogenous leukemia, Cytoplasmic antigen antibodies, Eosinophilia, Hla-b8, Hla-dr3, Hla-drw52, Htlv-1
Iatrogenic	Bacillus calmette-guérin vaccine
Infectious Disease	Coxsackie b virus, Echovirus, Hepatitis b vaccine, Hiv, Htlv-1, Hypertrichosis, Parvovirus, Pyrexia of unknown origin, Sterile pneumonitis, Streptococcus, Toxoplasma
Musculoskeletal/Orthopedic	Ectopic calcification, Electromyogram abnormalities, Muscular hypertrophy, Myositis, Periorbital swelling, Proximal muscle weakness, Proximal myopathy
Neurologic	Hyporeflexia
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	Ovarian cancer
Oncologic	Anti–tumor necrosis factor drugs, Breast cancer, Chronic myelogenous leukemia, Lung cancer, Ovarian cancer, Tumor necrosis factor polymorphisms
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	Lung cancer, Pulmonary fibrosis, Respiratory failure type 2, Sterile pneumonitis
Renal/Electrolyte	Rhabdomyolysis
Rheumatology/Immunology/Allergy	Immunocompromise, Rheumatoid factor positive
Sexual	Hiv
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

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