Sandbox: ESC guidelines
Overview
The Class designation is used to indicate whether a therapy is recommended or not and the certainty surrounding that recommendation.
Classes of Recommendation
Class I:
Conditions for which there is evidence and/or general agreement that a given procedure or treatment is beneficial, useful, and effective.
Class II:
Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment.
Class IIa:
Weight of evidence/opinion is in favor of usefulness/efficacy.
Class IIb:
Usefulness/efficacy is less well established by evidence/opinion.
Class III
Conditions for which there is evidence and/or general agreement that a procedure/treatment is not useful/effective and in some cases may be harmful.
Level Of Evidence
Level of Evidence A:
Data derived from multiple randomized clinical trials or meta-analyses of such studies.
Level of Evidence B:
- Data derived from one or more randomized trials or meta-analysis of such studies.
- Data derived from one or more non-randomized trials or meta-analysis of such studies.
Level of Evidence C:
- Non randomized observational studies with limitations in design or execution or Metanalysis of such studies.
- Consensus opinion of experts based on clinical experience.
