Sandbox: Pulmonary Valve regurgitation

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Overview

Historical Perspective

Epidemiology and Demographics

Classification

Pathophysiology

Causes

Congenital

Causes

Acquired

Causes

Chronic PR Acute PR
  • Quadricuspid or Bicuspid valves
  • Hypoplasia of the valves
  • Prolapse of the pulmonary valve
  • Infective endocarditis
  • Post repair of tetralogy of Fallot
  • Post repair of pulmonary valve stenosis
  • Rheumatic heart disease
  • Carinoid Syndrome
  • Myxomatous Degeneration of the pulmonary valve.
  • Following repair of tetralogy of Fallot
  • Following balloon or surgical valvulotomy or valvuloplasty for pulmonary stenosis
  • Absent pulmonary valve syndrome
  • Isolated congenital PR
  • Peripheral pulmonary artery stenosis
  • Pulmonary hypertension
  • Right ventricular outlet aneurysm
  • Neonatal Ebstein’s anomaly
  • Following balloon dilation of critical pulmonary stenosis
  • Perforation of valvar pulmonary atresia

History and Symptoms

Physical Examination

The physical examination findings in significant pulmonary regurgitation include:

  • Soft diastolic, decrescendo murmur best heard in the left upper sternal region, and increases in intensity with inspiration.
  • It can accompanied by a systolic ejection murmur.
  • Right ventricular heave is present when the right ventricle is enlarged.

Treatment