Empyema classification

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Empyema Microchapters

Patient Information

Overview

Classification

Subdural empyema
Pleural empyema

Differential Diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Classification

Empyema may be classified according to the etiology, anatomical location, and pathological course of the disease as follows:

Primary vs secondary empyema

Primary empyema occurs most commonly as iatrogenic empyema without associated pneumonia whereas secondary empyema happens more commonly secondary to pneumonia.

Empyema necessitans

Empyema necessitans is a spontaneous discharge of an empyema that has burrowed through the parietal pleura into the chest wall to form a subcutaneous abscess that may eventually rupture through the skin.

Stages of empyema

Empyema may be classified according to the stage of the disease as follows:

  • Exudative

In the exudative stage, the pus accumulates, and initial sterile fluid becomes infected with fluid characteristics of;

    • glucose>60
    • pH>7.2
    • LDH<500
  • Fibrinopurulent

During this stage, bacterial multiplies with increase in polymorphs and fibrin deposition on both pleural surfaces with fluid characteristics of;

    • glucose<40
    • pH <7.2
    • LDH>1000
  • Organizing

This stage is characterized by loculations, inelastic membranous peel, and lung entrapment as a result of scarring of the pleural space.


Tuberculous vs nontuberculous empyema

References