IDSA guidelines classification scheme
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Strength of Recommendations
Class A
Good evidence to support a recommendation for or against use.
Class B
Moderate evidence to support a recommendation for or against use.
Class C
Poor evidence to support a recommendation.
Quality of Evidence
Level of Evidence I
Evidence from ≥1 properly randomized, controlled trial.
Level of Evidence II
Evidence from ≥1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from >1 center); from multiple time-series; or from dramatic results from uncontrolled experiments.
Level of Evidence III
Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees.
Applying Strength of Recommendations and Quality of Evidence
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IDSA Updated Guidelines Classification Scheme 2016
Level of Evidence
Strong
Moderate
Low
Very Low
Strength of Recommendation
