Cystitis future or investigational therapies

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Pulsed radiofrequency (PRF) treatment of the superior hypogastric plexus may replace conventional treatment invasive and on invasive modalities. It is responsible for providing superior hypogastric plexus with nondestructive modulation, so that majority of the pain signals are transferred from the pelvic viscera.[1]

Hyperbaric Oxygen is used to treat hemorrhagic cystitis associated with exposure to radiation.[2] Hyperbaric Oxygen may also be helpful in treating emphysematous cystitis as presence of gas in the bladder wall interferes with the tissue oxygenation and proper oxygenation may help to curtail the associated damage. <ref name="pmid26331400">Garde H, Useros E, Hernando A, Chávez C, Paños E, Quijano P; et al. (2015). "[Emphysematous cystitis: Report of 2 cases with different outcomes]". Arch Esp Urol. 68 (7): 627–32. PMID 26331400. </ref

Discontinuation of the drug causing cystitis is the first approach. Similarly in case of a foreign body like stone etc,that is leading to cystitis, removal is performed. The associated conditions like BPH etc have to be treated to make sure that the patient does not have to face recurrence of Urinary Tract Infection.

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