Peritonitis epidemiology and demographics

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Peritonitis Main Page

Patient Information

Overview

Causes

Classification

Spontaneous Bacterial Peritonitis
Secondary Peritonitis

Differential Diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shivani Chaparala M.B.B.S [2]

Overview

Epidemiology and Demographics

Prevalence of SBP[1]

  • The prevalence of SBP in cirrhotic patients with ascites admitted to the hospital ranges from 10%-30%.
  • About 50% of cases are present at the time of hospitalization and 50% develop during the hospitalization.

Incidence of SBP

In hospitalized patients

  • Studies have demonstrated a 12% incidence of spontaneous bacterial peritonitis in patients admitted with decompensated cirrhosis.

In outpatient clinic ED setting

  • 2 studies examining asymptomatic patients presenting for a therapeutic paracentesis showed a combined 2.5% incidence of spontaneous bacterial peritonitis (defined as absolute neutrophil count >250 cells/mm3) in 545 patients.[2][3]

Mortality rate of SBP

  • The in-hospital mortality for SBP ranges from 10%-50% depending on various factors.
  • Mortality is 20% even in treated SBP patients
  • Overall one-year mortality rate after a first episode of SBP is 30%-93% regardless of its recurrence.

Age

  • The maximum incidence of SBP was in age group of 41–50 years and the mean age of presentation was 49 years.

Gender

  • Male are more commonly affected with SBP probably due to increased alcohol intake leading to cirrhosis.

References

  1. Bunchorntavakul C, Chamroonkul N, Chavalitdhamrong D (2016). "Bacterial infections in cirrhosis: A critical review and practical guidance". World J Hepatol. 8 (6): 307–21. doi:10.4254/wjh.v8.i6.307. PMC 4766259. PMID 26962397.
  2. Evans, L (2003). "Spontaneous bacterial peritonitis in asymptomatic outpatients with cirrhotic ascites". Hepatology. 37 (4): 897–901. doi:10.1053/jhep.2003.50119. ISSN 0270-9139.
  3. Chinnock, Brian; Afarian, Hagop; Minnigan, Hal; Butler, Jack; Hendey, Gregory W. (2008). "Physician Clinical Impression Does Not Rule Out Spontaneous Bacterial Peritonitis in Patients Undergoing Emergency Department Paracentesis". Annals of Emergency Medicine. 52 (3): 268–273. doi:10.1016/j.annemergmed.2008.02.016. ISSN 0196-0644.

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