Helicobacter pylori infection medical therapy

Helicobacter pylori infection Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Medical Therapy

Primary Treatment for H.pylori Infection

Primary Therapy	Sequential Therapy
PPI + Clarithromycin + Amoxicillin or metronidazole (Clarithromycin-based triple therapy) 14 days or PPI or H2RA + Bismuth + Metronidazole + Tetracycline (Bismuth quadruple therapy) 10-14days	PPI + Amoxicillin 5 days Followed by PPI + Clarithromycin + Tinidazole Additional 5 days (Alternative to clarithromycin-based triple or bismuth quadruple therapy)
Recommended treatment in the United States	Requires validation in the United States before it can be recommended as a first line therapy