Helicobacter pylori infection natural history, complications and prognosis
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Helicobacter pylori infection Microchapters |
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Differentiating Helicobacter pylori infection from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Natural History
If left untreated, H.pylori infection may progress to develop
- Gastritis which can be acute or chronic
- Peptic ulcer disease
Complications
Common complications of H.pylori infection include:[1]
- Gastric and duodenal ulcers
- Gastric adenocarcinoma
- MALT lymphoma
- Pseudomembranous colitis following H.pylori treatment
Prognosis
- Prognosis is generally regarded as good.
- H.pylori is associated with less than 1% risk of gastric MALT lymphoma and 1-2% lifetime risk of stomach cancer.[2]
References
- ↑ Hung IF, Wong BC (2009). "Assessing the risks and benefits of treating Helicobacter pylori infection". Therap Adv Gastroenterol. 2 (3): 141–7. doi:10.1177/1756283X08100279. PMC 3002520. PMID 21180540.
- ↑ Kusters JG, van Vliet AH, Kuipers EJ (2006). "Pathogenesis of Helicobacter pylori infection". Clin Microbiol Rev. 19 (3): 449–90. doi:10.1128/CMR.00054-05. PMC 1539101. PMID 16847081.