Splenic abscess

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Articles
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Evidence Based Medicine
Cochrane Collaboration on Splenic abscess Bandolier on Splenic abscess TRIP on Splenic abscess
Clinical Trials
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Guidelines / Policies / Govt
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Commentary
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Definitions
Definitions of Splenic abscess
Patient Resources / Community
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Healthcare Provider Resources
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Continuing Medical Education (CME)
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List of terms related to Splenic abscess

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Venkata Sivakrishna Kumar Pulivarthi M.B.B.S [2]

Synonyms and keywords:Abscess of spleen

Overview

Splenic abscess is an uncommon and lifethreatening condition. Clinical presentation, etiological factors, natural history, treatment and prognosis depends on whether the abscess was solitary or multiple. It is always fatal if left untreated. Most commonly associate with immunodeficient patients especially, hematological disorders such as leukemia, sickle cell disease etc.

Definition

Splenic abscess is defined as any infectious suppurative process involving identifiable macroscopic filling defects either in the parenchyma of the spleen or the subcapsular space.

Historical Perspective

• Since the times of Hippocrates, splenic abscess has been reported several times and he described the natural history and prognosis of splenic abscess.
• In the early days of 20th century, splenic abscess most commonly caused by typhoid and then followed by malaria.
• Ooi et al. described significant etiological differences such increase in the percentage of abscess cases due to aenarobics as compared to aerobics (7 vs 18-28%), fungi (1 vs 18-41%) as well as Mycobacterium tuberculosis (0.8 vs. 14%) in the second half of 20th century.