Fibroadenoma differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Fibroadenoma must be differentiated from other diseases that cause a similar clinical presentation, such as phyllodes tumor, hamartoma, and adenomyoepithelioma.>[1][2]
Differentiating Fibroadenoma from other Diseases
Fibroadenoma must be differentiated from other diseases that cause breast pain and swelling as shown below:[3][4] [5][6][7][8][9][10][11][12]
| Diseases | Laboratory Findings | Physical Examination | History and Symptoms | Other Findings | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Breast milk culture | Biopsy | Breast tenderness | Skin induration | Cordlike vein appearance | History of trauma | Nipple retraction | Nipple discharge | Erythema | Fever | Warmth | Lymphadenopathy | Itching | ||
| Breast abscess | + for bacteria | ✘ | ✔ | ✔ | ✘ | ✔ | ✘ | ✔ | ✔ | ✔ | ✔ | ✘ | ✘ | |
| Mastitis | + for bacteria | ✘ | ✔ | ✘ | ✔ | ✘ | ✔ | ✔ | ✔ | ✔ | ✔ | ✘ | ||
| Inflammatory breast cancer | ✘ | ✔ | ✔ | ✔ | ✘ | ✔ | ✘ | ✔ | ✘ | ✔ | ✔ | ✔ | *Peau d' orange appearance of the skin
*Metastasis is common. | |
| Galactocele | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ✔ | ✘ | ✘ | ✘ | ✘ | ✘ | It is differentiated from other masses by US. | |
| Plugged duct | ✘ | ✘ | ✔ | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ||
| Mondor's syndrome | ✔ | ✔ | ✔ | ✘ | Retracted breast skin and elevation of the skin may be observed. | |||||||||
| Cellulitis | ✘ | ✔ | ✔ | ✔ | ✘ | ✔ | ✔ | ✘ | ||||||
| Fibroadenoma | ✘ | ✔ | ✘ | ✘ | ✘ | ✘ | ✔ | *Peau d' orange skin apperance.
*Enlarged veins on the skin | ||||||
- Fibroadenoma must be differentiated from other diseases that cause a similar clinical presentation, such as:[1][2]
- Phyllodes tumor
- Fibrocystic breast changes
- Hamartoma
- Papillary carcinoma
- Pseudoangiomatous stromal hyperplasia
- Adenomyoepithelioma
References
- ↑ 1.0 1.1 Fibroadenoma. Libre Pathology (2015) http://librepathology.org/wiki/index.php/Fibroadenoma Accessed on January, 29 2016
- ↑ 2.0 2.1 Breast-nonmalignant-Fibroadenoma. PathologyOutlines (2015) http://www.pathologyoutlines.com/topic/breastfibroadenoma.html Accessed on January, 29 2016
- ↑ Greydanus DE, Matytsina L, Gains M (2006). "Breast disorders in children and adolescents". Prim Care. 33 (2): 455–502. doi:10.1016/j.pop.2006.02.002. PMID 16713771.
- ↑ Jahanfar S, Ng CJ, Teng CL (2013). "Antibiotics for mastitis in breastfeeding women". Cochrane Database Syst Rev (2): CD005458. doi:10.1002/14651858.CD005458.pub3. PMID 23450563.
- ↑ Lam E, Chan T, Wiseman SM (2014). "Breast abscess: evidence based management recommendations". Expert Rev Anti Infect Ther. 12 (7): 753–62. doi:10.1586/14787210.2014.913982. PMID 24791941.
- ↑ Kleer CG, van Golen KL, Merajver SD (2000). "Molecular biology of breast cancer metastasis. Inflammatory breast cancer: clinical syndrome and molecular determinants". Breast Cancer Res. 2 (6): 423–9. doi:10.1186/bcr89. PMC 138665. PMID 11250736.
- ↑ Dawood S, Merajver SD, Viens P, Vermeulen PB, Swain SM, Buchholz TA; et al. (2011). "International expert panel on inflammatory breast cancer: consensus statement for standardized diagnosis and treatment". Ann Oncol. 22 (3): 515–23. doi:10.1093/annonc/mdq345. PMC 3105293. PMID 20603440.
- ↑ Jaiyesimi IA, Buzdar AU, Hortobagyi G (1992). "Inflammatory breast cancer: a review". J Clin Oncol. 10 (6): 1014–24. doi:10.1200/JCO.1992.10.6.1014. PMID 1588366.
- ↑ Indelicato DJ, Grobmyer SR, Newlin H, Morris CG, Haigh LS, Copeland EM; et al. (2006). "Delayed breast cellulitis: an evolving complication of breast conservation". Int J Radiat Oncol Biol Phys. 66 (5): 1339–46. doi:10.1016/j.ijrobp.2006.07.1388. PMID 17126205.
- ↑ Belleflamme M, Penaloza A, Thoma M, Hainaut P, Thys F (2012). "Mondor disease: a case report in ED". Am J Emerg Med. 30 (7): 1325.e1–3. doi:10.1016/j.ajem.2011.06.031. PMID 21855258.
- ↑ Shetty MK, Watson AB (2001). "Mondor's disease of the breast: sonographic and mammographic findings". AJR Am J Roentgenol. 177 (4): 893–6. doi:10.2214/ajr.177.4.1770893. PMID 11566698.
- ↑ Kadioglu H, Yildiz S, Ersoy YE, Yücel S, Müslümanoğlu M (2013). "An unusual case caused by a common reason: Mondor's disease by oral contraceptives". Int J Surg Case Rep. 4 (10): 855–7. doi:10.1016/j.ijscr.2013.07.026. PMC 3785854. PMID 23959419.