Syphilis other diagnostic studies
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]
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Overview
Other diagnostic studies which may help diagnose complications of syphilis are CSF examination, screening tests for other STIs such as HIV, chlamydia, gonorrhea, and biopsy.[1][2]
Other Diagnostic Studies
Other diagnostic studies which may help diagnose complications of syphilis are:[1][2]
CSF examination
- May help to diagnose neurosyphilis
- Includes CSF cell count or protein and a reactive CSF-VDRL or CSF FTA-ABS test
- CSF-VDRL is highly specific but insensitive
- CSF FTA-ABS test is less specific for neurosyphilis than the CSF-VDRL but is highly sensitive
Screening tests for other STIs
Biopsy
Biopsy may be considered if clinical findings do not correlate with negative serological tests and there is a strong index of suspicion for syphilis.
References
- ↑ 1.0 1.1 http://www.cdc.gov/std/tg2015/syphilis.htm accessed on September 28, 2016
- ↑ 2.0 2.1 Luger AF, Schmidt BL, Kaulich M (2000). "Significance of laboratory findings for the diagnosis of neurosyphilis". Int J STD AIDS. 11 (4): 224–34. PMID 10772085.