Tropical sprue history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

History and Symptoms

Tropical sprue is diagnosed based on the following criteria:

• Compatible clinical presentation
• Presence of malabsorption for two different substances
• Abnormal small intestinal histological findings
• Exclusion of other causes of malabsorption
• Response to treatment with tetracycline and folic acid

Patients with tropical sprue present with the symptoms of:

• Visit to a tropical region
• Chronic diarrhea
• Anorexia
• Weight loss
• Malnutrition
• Anemia
• Fatigue
• Neuropathy
• Bone pain due to calcium and vitamin D malabsorption
• Weakness in combing hair and getting up from the chair suggesting a proximal muscle weakness