Heat stroke natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Natural History

Complications

The complications of heat stroke include:[1][2]

Life Threatening complications

  • Syndrome of multiorgan dysfunction
  • Acute renal failure
  • Myocardial injury
  • Disseminated intravascular coagulation (DIC)

Common Complications

  • Dehydration
  • Electrolyte disturbances
  • Encephalopathy
  • Acute respiratory distress syndrome
  • Hepatocellular damage
  • Rhabdomyolysis
  • Acute renal failure
  • Myocardial injury
  • Hematologic complications
    • Disseminated intravascular coagulation (DIC)
    • Thrombocytopenia

Rare Complications

The rare complications include:[1][2]

  • Bowel ischemia or infarction
  • Pancreatic injury

Prognosis

The revival of the functioning of the central nervous system is a positive prognostic sign. It is usually seen following aggressive therapy. 20% patients face residual damage of the brain and a higher mortality is associated with this.[3][4]

References

  1. 1.0 1.1 Masood U, Sharma A, Syed W, Manocha D (2016). "Bowel Ischemia from Heat Stroke: A Rare Presentation of an Uncommon Complication". Case Rep Med. 2016: 5217690. doi:10.1155/2016/5217690. PMC 5093235. PMID 27840645.
  2. 2.0 2.1 al-Mashhadani SA, Gader AG, al Harthi SS, Kangav D, Shaheen FA, Bogus F (1994). "The coagulopathy of heat stroke: alterations in coagulation and fibrinolysis in heat stroke patients during the pilgrimage (Haj) to Makkah". Blood Coagul Fibrinolysis. 5 (5): 731–6. PMID 7865679.
  3. Hart GR, Anderson RJ, Crumpler CP, Shulkin A, Reed G, Knochel JP (1982). "Epidemic classical heat stroke: clinical characteristics and course of 28 patients". Medicine (Baltimore). 61 (3): 189–97. PMID 7078400.
  4. Dematte JE, O'Mara K, Buescher J, Whitney CG, Forsythe S, McNamee T; et al. (1998). "Near-fatal heat stroke during the 1995 heat wave in Chicago". Ann Intern Med. 129 (3): 173–81. PMID 9696724.