Toxoplasmosis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Natural History, Complications and Prognosis

Natural History

During the first few weeks, the infection typically causes a mild flu-like illness or no illness. After the first few weeks of infection have passed, the parasite rarely causes any symptoms in otherwise healthy adults. However, people with a weakened immune system, such as those infected with HIV, and fetuses, may become seriously ill, and it can occasionally be fatal. The parasite can cause encephalitis (inflammation of the brain) and neurologic diseases and can affect the heart, liver, and eyes (chorioretinitis).

Complications

Complications that can develop as a result of toxoplasmosis are

Congenital toxoplasmosis

Mental retardation
Seizures
Motor difficulties
Severe vision loss
Hydrocephalus or microcephalus
hearing loss.^[1]

Infection in AIDS/immunocomprimised individuals

Infection in immunocompetent individuals

Blindness

References

↑ Webster, Joanne P.; Stillwaggon, Eileen; Carrier, Christopher S.; Sautter, Mari; McLeod, Rima (2011). "Maternal Serologic Screening to Prevent Congenital Toxoplasmosis: A Decision-Analytic Economic Model". PLoS Neglected Tropical Diseases. 5 (9): e1333. doi:10.1371/journal.pntd.0001333. ISSN 1935-2735.

Template:WikiDoc Sources

[WebsterStillwaggon2011-1] Webster, Joanne P.; Stillwaggon, Eileen; Carrier, Christopher S.; Sautter, Mari; McLeod, Rima (2011). "Maternal Serologic Screening to Prevent Congenital Toxoplasmosis: A Decision-Analytic Economic Model". PLoS Neglected Tropical Diseases. 5 (9): e1333. doi:10.1371/journal.pntd.0001333. ISSN 1935-2735.

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