Hyperkalemia laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]

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Laboratory Findings

In a patient who does not have a risk for hyperkalemia, repeating the blood test is indicated before taking any actions unless changes are present on electrocardiography.

Initial tests

• Complete blood count (CBC)
• Metabolic profile
• Urine potassium, sodium, and osmolality

Cause specific

• Blood glucose In patients with history of diabetes mellitus
• Digoxin level
• Arterial or venous blood gas (acidosis)
• Urinalysis (renal insufficiency)
• Serum cortisol and aldosterone levels (mineralocorticoid deficiency)
• Serum uric acid and phosphorus assays (tumor lysis syndrome)
• Serum creatinine phosphokinase (CPK) and calcium measurements and urine myoglobin test (crush injury or rhabdomyolysis)