Toxoplasmosis differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Disease	Differentiating signs and symptoms	Differentiating tests
CNS lymphoma		Brain biopsy
Metastatic brain tumor
Mycobacterial CNS	Prior history of residence in an endemic area. Chroniccough, weight loss, hemoptysis	PCR of CSF for tuberculosis Mycobacterial culture of CSF Brain biopsy for acid-fast bacilli staining andculturstain and culture may be positive for acid-fast bacilli, and CXR may show cavitations if pulmonary disease also present.
Aspergillosis	Pulmonary lesions in addition to CNS lesions. Symptoms may include cough, chest pain, and hemoptysis.	CSF fungal culture, galactomannan.
Cryptococcosis
Chaga's disease
CMV infection
HSV infection
VZ infection
Bacterial abscess
Progressive multifocal leukoencephalopathy
Cat Scratch Disease