Cryptococcosis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Serge Korjian M.D.; Yazan Daaboul, M.D.
Overview
The symptoms of cryptococcosis depend on the site of infection/clinical syndrome, the virulence of the yeast strain and the immune status of the host. Patients may be completely asymptomatic, or may have latent infection or symptomatic disease. Because cryptococcus enters the body through the respiratory route, infection can present as pneumonia-like illness with fever, cough, sputum production and chest pain. Cryptococcus can also disseminate to the central nervous system and cause meningoencephalitis presenting with headache, nausea, vomiting, altered sensorium and focal neurological deficits.
Symptoms
The symptoms of cryptococcosis depend on the site of infection/clinical syndrome, the virulence of the yeast strain and the immune status of the host. Patients may be completely asymptomatic, or may have latent infection or symptomatic disease. Because cryptococcus enters the body through the respiratory route, infection can present as pneumonia-like illness. Cryptococcus can also disseminate to the central nervous system and cause meningoencephalitis.
Cryptococcal Pneumonia
- Cough
- Shortness of breath
- Chest pain
- Fever
Cryptococcal meningitis
- Headache
- Fever
- Neck pain
- Nausea and vomiting
- Sensitivity to light
- Confusion