Hirschsprung's disease natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
If left untreated, Hirschsprung disease can lead to enterocolitis and death. Common complications include enterocolitis, intestinal perforation and short bowel syndrome. After appropriate surgical intervention, mortality drops significantly.
Natural history
If left untreated, Hirschsprung disease can lead to enterocolitis and death.
Complications
- Inflammation and infection of the intestines (enterocolitis).[1]
- Intestinal perforation
- Short bowel syndrome, a condition that can lead to malnourishment and dehydration
Possible complications of surgery include
- Wound infection
- Anastomotic leakage
- Intestinal obstruction
- Pelvic abscess
- Chronic obstructive symptoms
- Chronic constipation or diarrhea
Prognosis
- Hirschsprung disease can lead to mortality in up to 80% of cases.
- After appropriate surgical intervention, mortality drops to 30 %.