Acute viral nasopharyngitis historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Historical Perspective
- In the 18th century, Benjamin Franklin considered the causes and prevention of the common cold.
- After several years of research he concluded: "People often catch cold from one another when shut up together in small close rooms, coaches and when sitting near and conversing so as to breathe in each other's transpiration."
- Although viruses had not yet been discovered, Franklin hypothesized that the common cold was passed between people through the air.
- He recommended exercise, bathing, and moderation in food and drink consumption to avoid the common cold.[1] Franklin's theory on the transmission of the cold was confirmed some 150 years later.[2]
Common Cold Unit
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In the United Kingdom, the Common Cold Unit was set up by the civilian Medical Research Council in 1946 . The unit worked with volunteers who were infected with various viruses.[3] The rhinovirus was discovered there. In the late 1950s, researchers were able to grow one of these cold viruses in a tissue culture, as it would not grow in fertilized chicken eggs, the method used for many other viruses. In the 1970s, the CCU demonstrated that treatment with interferon during the incubation phase of rhinovirus infection protects somewhat against the disease, but no practical treatment could be developed. The unit was closed in 1989, two years after it completed research of zinc gluconate lozenges in the prophylaxis and treatment of rhinovirus colds.[4]
References
- ↑ "Scientist and Inventor: Benjamin Franklin: In His Own Words... (AmericanTreasures of the Library of Congress)".
- ↑ Andrewes CH, Lovelock JE, Sommerville T (1951). "An experiment on the transmission of colds". Lancet. 1 (1): 25–7. PMID 14795755.
- ↑ Reto U. Schneider (2004). Das Buch der verrückten Experimente (Broschiert). ISBN 344215393X.
- ↑ Al-Nakib, W (1987). "Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges". J Antimicrob Chemother. 20 (6): 893–901. PMID 3440773. Unknown parameter
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