Acute viral nasopharyngitis historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Common cold was first considered by Benjamin Franklin in the 18th century.
Historical Perspective
- In the 18th century, Benjamin Franklin considered the causes and prevention of the common cold.
- After several years of research he concluded: "People often catch a cold from one another when shut up together in small close rooms, coaches and when sitting near and conversing so as to breathe in each other's transpiration."
- Although viruses had not yet been discovered, Franklin hypothesized that the common cold was passed between people through the air.
- He recommended exercise, bathing, and moderation in food and drink consumption to avoid the common cold.[1] Franklin's theory on the transmission of the cold was confirmed some 150 years later.[2]
Common Cold Unit
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- In the United Kingdom, the Common Cold Unit was set up by the civilian Medical Research Council in 1946. The unit worked with volunteers who were infected with various viruses.[3]
- The rhinovirus was discovered there. In the late 1950s, researchers were able to grow one of these cold viruses in a tissue culture, as it would not grow in fertilized chicken eggs, the method used for many other viruses.
- In the 1970s, the CCU demonstrated that treatment with interferon during the incubation phase of rhinovirus infection protects somewhat against the disease, but no practical treatment could be developed.
- The unit was closed in 1989, two years after it completed research of zinc gluconate lozenges in the prophylaxis and treatment of rhinovirus colds.[4]
References
- ↑ "Scientist and Inventor: Benjamin Franklin: In His Own Words... (AmericanTreasures of the Library of Congress)".
- ↑ Andrewes CH, Lovelock JE, Sommerville T (1951). "An experiment on the transmission of colds". Lancet. 1 (1): 25–7. PMID 14795755.
- ↑ Reto U. Schneider (2004). Das Buch der verrückten Experimente (Broschiert). ISBN 344215393X.
- ↑ Al-Nakib, W (1987). "Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges". J Antimicrob Chemother. 20 (6): 893–901. PMID 3440773. Unknown parameter
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