Psittacosis laboratory tests
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Psittacosis Microchapters |
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Diagnosis |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Exposure history is paramout to diagnosis. Bloodwork shows leukopenia, thrombocytopenia and moderately elevated liver enzymes.
Laboratory Findings
Electrolyte and Biomarker Studies
- Leukocytosis
- Rise in ESR
- Rise in CRP
- Liver enzymes elevated
- Hyponatremia may be noticed
- Rise in blood urea nitrogen levels
- Urinalysis may show proteinuria
Culture
Culture of C psittaci is demanding, requires a level 3 laboratory isolation facility because of the risk of laboratory transmission and is rarely performed.
Serology
Serology is the most widely available method for laboratory diagnosis of C psittaci infection. Complement fixation, microimmunofluorescence, and EIA the most commonly used techniques.
Nucleic Acid Amplification
PCR techniques have been utilized in outbreaks for several years and can give a rapid, specific diagnosis, which is particularly important in severe infection.