Dermatophytosis other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Most of the time, ringworm can be diagnosed by looking at the skin. Other diagnostic studies that can be used to diagnose dermatophytosis are matrix-assisted laser desorption ionization-time of flight mass and reflectance confocal microscopy.
Other Diagnostic Studies
Other diagnostic studies to confirm dermatophytosis may include:
Matrix-assisted laser desorption ionization-time of flight mass spectrometry
- It is based on the detection of biochemical characteristics of a proteolytic degradation product which is a product of mycological infections or noninfectious diseases.
- Dermatophytes are represented by proteolytic degradation products of native proteins.
- The peptide patterns of affected samples are compared with those of known samples containing peptide spectra from skin disorders stored in an already existing database.
- It is a time efficient process, as it enables simultaneous identification of up to 64 dermatophyte strains, with results coming back within 24 hours.
Reflectance confocal microscopy
- It provides in vivo imaging of the epidermis and superficial dermis at a high resolution and can be used to detect cutaneous fungi and parasitic infestations.
- Branching fungal hyphae can be visualized over an erythematous, annular, scaly patch.